Metabolic Risk Susceptibility in Men Is Partially Related to AdiponectinLeptin Ratio
Joint Authors
Vega, Gloria Lena
Grundy, Scott M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
High adiponectin/leptin ratio may be protective from metabolic risks imparted by high triglyceride, low HDL, and insulin resistance.
Methods.
This cross-sectional study examines plasma adipokine levels in 428 adult men who were subgrouped according to low (<6.5 μg/mL)and high (≥6.5 μg/mL)adiponectin levels or a low or high ratio of adiponectin/leptin.
Results.
Men with high adiponectin/leptin ratio had lower plasma triglyceride and higher HDL cholesterol than those with low ratio.
Similarly, those with high adiponectin/leptin ratio had lower TG/HDL cholesterol ratio and HOMA2-IR than those with low ratio.
In contrast, levels of adiponectin or the ratio of adiponectin/leptin did not associate with systolic blood pressure.
But the ratio of adiponectin/leptin decreased progressively with the increase in the number of risk factors for metabolic syndrome.
Conclusion.
Adipokine levels may reflect adipose tissue triglyceride storage capacity and insulin sensitivity.
Leptin is an index of fat mass, and adiponectin is a biomarker of triglyceride metabolism and insulin sensitivity.
Men with high adiponectin/leptin ratios have better triglyceride profile and insulin sensitivity than men with a low ratio regardless of waist girth.
American Psychological Association (APA)
Vega, Gloria Lena& Grundy, Scott M.. 2013. Metabolic Risk Susceptibility in Men Is Partially Related to AdiponectinLeptin Ratio. Journal of Obesity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-469909
Modern Language Association (MLA)
Vega, Gloria Lena& Grundy, Scott M.. Metabolic Risk Susceptibility in Men Is Partially Related to AdiponectinLeptin Ratio. Journal of Obesity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-469909
American Medical Association (AMA)
Vega, Gloria Lena& Grundy, Scott M.. Metabolic Risk Susceptibility in Men Is Partially Related to AdiponectinLeptin Ratio. Journal of Obesity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-469909
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469909