Preparation of Biodegradable Silk FibroinAlginate Blend Films for Controlled Release of Antimicrobial Drugs
Joint Authors
Baimark, Yodthong
Srisuwan, Yaowalak
Source
Advances in Materials Science and Engineering
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Engineering Sciences and Information Technology
Abstract EN
Silk fibroin (SF)/alginate blend films have been prepared for controlled release of tetracycline hydrochloride, an antimicrobial model drug.
The blend films were analysed by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and UV-vis spectroscopy.
The functional groups of the SF/alginate blends were monitored from their FTIR spectra.
The homogeneity of the blend films was observed from SEM images.
The dissolution and film transparency of the blend films depended on the SF/alginate blend ratio.
The in vitro drug release profile of the blend films was determined by plotting the cumulative drug release versus time.
It was found that the drug release significantly decreased as the SF/alginate blend ratio increased.
The results demonstrated that the SF/alginate blend films should be a useful controlled-release delivery system for water-soluble drugs.
American Psychological Association (APA)
Srisuwan, Yaowalak& Baimark, Yodthong. 2013. Preparation of Biodegradable Silk FibroinAlginate Blend Films for Controlled Release of Antimicrobial Drugs. Advances in Materials Science and Engineering،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-470055
Modern Language Association (MLA)
Srisuwan, Yaowalak& Baimark, Yodthong. Preparation of Biodegradable Silk FibroinAlginate Blend Films for Controlled Release of Antimicrobial Drugs. Advances in Materials Science and Engineering No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-470055
American Medical Association (AMA)
Srisuwan, Yaowalak& Baimark, Yodthong. Preparation of Biodegradable Silk FibroinAlginate Blend Films for Controlled Release of Antimicrobial Drugs. Advances in Materials Science and Engineering. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-470055
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470055