Progenitors for the Corneal Endothelium and Trabecular Meshwork : A Potential Source for Personalized Stem Cell Therapy in Corneal Endothelial Diseases and Glaucoma
Joint Authors
Yu, Wing Yan
Sheridan, Carl
Kearns, Victoria
Mason, Sharon
Grierson, Ian
Lo, Amy Cheuk Yin
Wong, David
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-06
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Several adult stem cell types have been found in different parts of the eye, including the corneal epithelium, conjunctiva, and retina.
In addition to these, there have been accumulating evidence that some stem-like cells reside in the transition area between the peripheral corneal endothelium (CE) and the anterior nonfiltering portion of the trabecular meshwork (TM), which is known as the Schwalbe's Ring region.
These stem/progenitor cells may supply new cells for the CE and TM.
In fact, the CE and TM share certain similarities in terms of their embryonic origin and proliferative capacity in vivo.
In this paper, we discuss the putative stem cell source which has the potential for replacement of lost and nonfunctional cells in CE diseases and glaucoma.
The future development of personalized stem cell therapies for the CE and TM may reduce the requirement of corneal grafts and surgical treatments in glaucoma.
American Psychological Association (APA)
Yu, Wing Yan& Sheridan, Carl& Grierson, Ian& Mason, Sharon& Kearns, Victoria& Lo, Amy Cheuk Yin…[et al.]. 2011. Progenitors for the Corneal Endothelium and Trabecular Meshwork : A Potential Source for Personalized Stem Cell Therapy in Corneal Endothelial Diseases and Glaucoma. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-470099
Modern Language Association (MLA)
Yu, Wing Yan…[et al.]. Progenitors for the Corneal Endothelium and Trabecular Meshwork : A Potential Source for Personalized Stem Cell Therapy in Corneal Endothelial Diseases and Glaucoma. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-470099
American Medical Association (AMA)
Yu, Wing Yan& Sheridan, Carl& Grierson, Ian& Mason, Sharon& Kearns, Victoria& Lo, Amy Cheuk Yin…[et al.]. Progenitors for the Corneal Endothelium and Trabecular Meshwork : A Potential Source for Personalized Stem Cell Therapy in Corneal Endothelial Diseases and Glaucoma. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-470099
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470099