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The Consequences of Chorioamnionitis : Preterm Birth and Effects on Development
Joint Authors
Moss, Timothy J. M.
Polglase, Graeme R.
Galinsky, Robert
Hooper, Stuart B.
Black, M. Jane
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Preterm birth is a major cause of perinatal mortality and long-term morbidity.
Chorioamnionitis is a common cause of preterm birth.
Clinical chorioamnionitis, characterised by maternal fever, leukocytosis, tachycardia, uterine tenderness, and preterm rupture of membranes, is less common than subclinical/histologic chorioamnionitis, which is asymptomatic and defined by inflammation of the chorion, amnion, and placenta.
Chorioamnionitis is often associated with a fetal inflammatory response.
The fetal inflammatory response syndrome (FIRS) is defined by increased systemic inflammatory cytokine concentrations, funisitis, and fetal vasculitis.
Clinical and epidemiological studies have demonstrated that FIRS leads to poor cardiorespiratory, neurological, and renal outcomes.
These observations are further supported by experimental studies that have improved our understanding of the mechanisms responsible for these outcomes.
This paper outlines clinical and experimental studies that have improved our current understanding of the mechanisms responsible for chorioamnionitis-induced preterm birth and explores the cellular and physiological mechanisms underlying poor cardiorespiratory, neural, retinal, and renal outcomes observed in preterm infants exposed to chorioamnionitis.
American Psychological Association (APA)
Galinsky, Robert& Polglase, Graeme R.& Hooper, Stuart B.& Black, M. Jane& Moss, Timothy J. M.. 2013. The Consequences of Chorioamnionitis : Preterm Birth and Effects on Development. Journal of Pregnancy،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-470112
Modern Language Association (MLA)
Galinsky, Robert…[et al.]. The Consequences of Chorioamnionitis : Preterm Birth and Effects on Development. Journal of Pregnancy No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-470112
American Medical Association (AMA)
Galinsky, Robert& Polglase, Graeme R.& Hooper, Stuart B.& Black, M. Jane& Moss, Timothy J. M.. The Consequences of Chorioamnionitis : Preterm Birth and Effects on Development. Journal of Pregnancy. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-470112
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470112