![](/images/graphics-bg.png)
Nutritional Risk Factors for Age-Related Macular Degeneration
Joint Authors
Hoyng, Carel B.
Kirchhof, Bernd
Fauser, Sascha
Lechanteur, Yara T.
Ristau, Tina
Ersoy, Lebriz
den Hollander, Anneke I.
Hahn, Moritz
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the role of nutritional factors, serum lipids, and lipoproteins in late age-related macular degeneration (late AMD).
Methods.
Intake of red meat, fruit, fish, vegetables, and alcohol, smoking status, and body mass index (BMI) were ascertained questionnaire-based in 1147 late AMD cases and 1773 controls from the European Genetic Database.
Serum levels of lipids and lipoproteins were determined.
The relationship between nutritional factors and late AMD was assessed using logistic regression.
Based on multivariate analysis, area-under-the-curve (AUC) was calculated by receiver-operating-characteristics (ROC).
Results.
In a multivariate analysis, besides age and smoking, obesity (odds ratio (OR): 1.44, P=0.014) and red meat intake (daily: OR: 2.34, P=8.22×10-6; 2–6x/week: OR: 1.67, P=7.98×10-5) were identified as risk factors for developing late AMD.
Fruit intake showed a protective effect (daily: OR: 0.52, P=0.005; 2–6x/week: OR: 0.58, P=0.035).
Serum lipid and lipoprotein levels showed no significant association with late AMD.
ROC for nutritional factors, smoking, age, and BMI revealed an AUC of 0.781.
Conclusion.
Red meat intake and obesity were independently associated with increased risk for late AMD, whereas fruit intake was protective.
A better understanding of nutritional risk factors is necessary for the prevention of AMD.
American Psychological Association (APA)
Ersoy, Lebriz& Ristau, Tina& Lechanteur, Yara T.& Hahn, Moritz& Hoyng, Carel B.& Kirchhof, Bernd…[et al.]. 2014. Nutritional Risk Factors for Age-Related Macular Degeneration. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470145
Modern Language Association (MLA)
Ersoy, Lebriz…[et al.]. Nutritional Risk Factors for Age-Related Macular Degeneration. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-470145
American Medical Association (AMA)
Ersoy, Lebriz& Ristau, Tina& Lechanteur, Yara T.& Hahn, Moritz& Hoyng, Carel B.& Kirchhof, Bernd…[et al.]. Nutritional Risk Factors for Age-Related Macular Degeneration. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470145
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470145