Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis
Joint Authors
Simonetti, Giovanni
Neroni, Luca
Nezzo, Marco
Manenti, Guglielmo
Altobelli, Simone
Floris, Roberto
Vasili, Erald
Antonicoli, Marco
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal fluid with high sensitive polymerase chain reaction.
The role of magnetic resonance imaging specifically in natalizumab-associated progressive multifocal leukoencephalopathy is strengthening, and it is gaining importance not only as an irreplaceable diagnostic tool but also as a surveillance and risk stratifying tool in treated patients.
While other imaging techniques such as computed tomography lack sensitivity and specificity, magnetic resonance performed with morphological and functional sequences offers clinicians the possibility to early identify the stage of the disease and the emergence of an immune reconstitution inflammatory syndrome after natalizumab blood removal plasmapheresis.
American Psychological Association (APA)
Manenti, Guglielmo& Altobelli, Simone& Nezzo, Marco& Antonicoli, Marco& Vasili, Erald& Neroni, Luca…[et al.]. 2013. Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis. Case Reports in Radiology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-470398
Modern Language Association (MLA)
Manenti, Guglielmo…[et al.]. Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis. Case Reports in Radiology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-470398
American Medical Association (AMA)
Manenti, Guglielmo& Altobelli, Simone& Nezzo, Marco& Antonicoli, Marco& Vasili, Erald& Neroni, Luca…[et al.]. Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis. Case Reports in Radiology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-470398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470398