Variations of Lipoprotein(a) Levels in the Metabolic Syndrome : A Report from the Maracaibo City Metabolic Syndrome Prevalence Study
Joint Authors
Martínez, María Sofía
Lubo, Adonías
Cabrera, Mayela
Cano, Raquel
Torres, Yaquelín
Mejías, José
Cano, Climaco
Salazar, Juan
Aguirre, Miguel
Bermúdez, Valmore
Rojas, Liliana
Chávez, Mervin
Bello, Luis
Mengual, Edgardo
Áñez, Roberto
Rojas, Joselyn
Sánchez de Rosales, Milagro
Montiel, María
París, Rafael
Quevedo, Ana
Toledo, Alexandra
Villalobos, Marjorie
Torres, Wheeler
Chacín, Maricarmen
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-22
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Lipoprotein(a) [Lp(a)] is a known risk factor for cardiovascular disease, yet its influence on metabolic syndrome (MS) is still controversial.
The purpose of this study was to assess the impact generated by this diagnosis in serum Lp(a) concentrations.
Materials and Methods.
A total of 1807 subjects of both genders (55.3% women and 44.7% men) belonging to the Maracaibo City Metabolic Syndrome Prevalence Study were evaluated.
Results were expressed as Mean ± SD, determining differences through Student’s t-test and One-Way ANOVA test.
Multiple logistic regression models were utilized for analyzing factors associated with elevated serum Lp(a) levels and MS.
Total cholesterol and LDL-C were corrected according to Lp(a)-Cholesterol when necessary.
Results.
No differences were found in Lp(a) values between genders; P=0,292.
The association between MS and the classification of Lp(a) was statistically significant (χ2=28.33; P<0,0001), with greater levels in subjects with this diagnosis.
In the univariate analysis, subjects with each of the separate diagnostic criteria showed higher serum Lp(a) concentrations, except for hyperglycemia.
Conclusions.
Lp(a) values exhibit important variations regarding MS and each of its components.
Impaired fasting glucose appeared as a protecting factor against elevated Lp(a) concentrations, whereas its association with LDL-C and hs-CRP suggests a potential pro-inflammatory role.
American Psychological Association (APA)
Bermúdez, Valmore& Rojas, Joselyn& Salazar, Juan& Bello, Luis& Áñez, Roberto& Toledo, Alexandra…[et al.]. 2013. Variations of Lipoprotein(a) Levels in the Metabolic Syndrome : A Report from the Maracaibo City Metabolic Syndrome Prevalence Study. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-470454
Modern Language Association (MLA)
Bermúdez, Valmore…[et al.]. Variations of Lipoprotein(a) Levels in the Metabolic Syndrome : A Report from the Maracaibo City Metabolic Syndrome Prevalence Study. Journal of Diabetes Research No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-470454
American Medical Association (AMA)
Bermúdez, Valmore& Rojas, Joselyn& Salazar, Juan& Bello, Luis& Áñez, Roberto& Toledo, Alexandra…[et al.]. Variations of Lipoprotein(a) Levels in the Metabolic Syndrome : A Report from the Maracaibo City Metabolic Syndrome Prevalence Study. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-470454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470454