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Surgical Management of Appendicular Skeletal Metastases in Thyroid Carcinoma
Joint Authors
Lewis, Valerae O.
Lin, Patrick P.
Harun, Nursat
Satcher, Robert L.
Moon, Bryan S.
Feng, Lei
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Bone is a frequent site of metastasis from thyroid carcinoma, but prognostic factors for patients who have surgery for thyroid carcinoma bone metastases are poorly understood.
Methods.
A retrospective review at a single institution identified 41 patients that underwent surgery in the appendicular skeleton for thyroid carcinoma bone metastasis from 1988 to 2011.
Results.
Overall patient survival probability by Kaplan-Meier analysis after surgery for bone metastasis was 72% at 1 year, 29% at 5 years, and 20% at 8 years.
Patients who had their tumor excised (P=0.001) or presented with solitary bone involvement had a lower risk of death following surgery adjusting for age and gender.
Disease progression at the surgery site occurred more frequently with a histological diagnosis of follicular carcinoma compared with other subtypes (P=0.023).
Multivariate analysis showed that tumor subtype, chemotherapy, and preoperative radiation treatment had no effect on survival after surgery.
Patients treated with radioactive iodine had better survival following thyroidectomy, but not following surgery for bone metastases.
Conclusions.
For patients undergoing surgery for thyroid cancer bone metastasis, resection of the bone metastasis, if possible, has a survival benefit.
American Psychological Association (APA)
Satcher, Robert L.& Lin, Patrick P.& Harun, Nursat& Feng, Lei& Moon, Bryan S.& Lewis, Valerae O.. 2012. Surgical Management of Appendicular Skeletal Metastases in Thyroid Carcinoma. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-470511
Modern Language Association (MLA)
Moon, Bryan S.…[et al.]. Surgical Management of Appendicular Skeletal Metastases in Thyroid Carcinoma. International Journal of Surgical Oncology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-470511
American Medical Association (AMA)
Satcher, Robert L.& Lin, Patrick P.& Harun, Nursat& Feng, Lei& Moon, Bryan S.& Lewis, Valerae O.. Surgical Management of Appendicular Skeletal Metastases in Thyroid Carcinoma. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-470511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470511