Low Resolution Limits and Inaccurate Algorithms Decrease Significantly the Value of Late Loss in Current Drug-Eluting Stent Trials
Joint Authors
Dahm, Johannes B.
van Buuren, Frank
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Quantitative coronary and vascular angiography (QCA resp., QVA) remains the current gold standard for evaluation of restenosis.
Late loss as one of the most commonly accepted parameters to highlight efficacy of the various devices has shown high correlation to clinical parameters but, surprisingly, has no impact on the evaluation of the remaining amount of restenostic tissue.
The current clinical practice leads to unrealistic late loss calculations.
Smaller late loss differences are usually not greater than the inherited resolution limits of QCA, which is especially the case in small differences between the various stents in the drug-eluting stent era.
Late loss include additional systematic and random errors, due to the fact that measurements were taken at two different time points including the inherited resolution and calibration limits of QCA on two occasions.
Due to the limited value of late loss in discriminating the small differences between the one and other DES, late lumen area loss and clearly defined calculation algorithms (e.g., MLD-relocation) should be used in future DES studies also to fulfill the more stringent regulatory requirements.
American Psychological Association (APA)
Dahm, Johannes B.& van Buuren, Frank. 2012. Low Resolution Limits and Inaccurate Algorithms Decrease Significantly the Value of Late Loss in Current Drug-Eluting Stent Trials. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-470526
Modern Language Association (MLA)
Dahm, Johannes B.& van Buuren, Frank. Low Resolution Limits and Inaccurate Algorithms Decrease Significantly the Value of Late Loss in Current Drug-Eluting Stent Trials. International Journal of Vascular Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-470526
American Medical Association (AMA)
Dahm, Johannes B.& van Buuren, Frank. Low Resolution Limits and Inaccurate Algorithms Decrease Significantly the Value of Late Loss in Current Drug-Eluting Stent Trials. International Journal of Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-470526
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470526