Technological Progress in Generation of Induced Pluripotent Stem Cells for Clinical Applications
Joint Authors
Cho, Kyung Jin
Lee, Chang Kyu
Cho, Ssang-Goo
Lee, Kyung-Ok
Oh, Seung-Ick
Hong, Sunghoi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is achieved by viral-mediated transduction of defined transcription factors.
Generation of iPSCs is of great medical interest as they have the potential to be a source of patient-specific cells.
For the eventual goal of clinical application, it is necessary to overcome the limitations of low reprogramming efficiency and chromosomal abnormalities due to viral DNA integration.
In this paper, we summarize the current state of reprogramming technology for generation of iPSCs and also discuss potential approaches to the development of safe iPSCs for personalized cell-based replacement therapy.
American Psychological Association (APA)
Oh, Seung-Ick& Lee, Chang Kyu& Cho, Kyung Jin& Lee, Kyung-Ok& Cho, Ssang-Goo& Hong, Sunghoi. 2012. Technological Progress in Generation of Induced Pluripotent Stem Cells for Clinical Applications. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470570
Modern Language Association (MLA)
Oh, Seung-Ick…[et al.]. Technological Progress in Generation of Induced Pluripotent Stem Cells for Clinical Applications. The Scientific World Journal No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-470570
American Medical Association (AMA)
Oh, Seung-Ick& Lee, Chang Kyu& Cho, Kyung Jin& Lee, Kyung-Ok& Cho, Ssang-Goo& Hong, Sunghoi. Technological Progress in Generation of Induced Pluripotent Stem Cells for Clinical Applications. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-470570
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470570