Evolutionary and Molecular Aspects of Indian Tomato Leaf Curl Virus Coat Protein
Joint Authors
Patel, Saumya K.
Kumar, Sivakumar Prasanth
Jasrai, Yogesh T.
Pandya, Himanshu A.
Kapopara, Ravi G.
Source
International Journal of Plant Genomics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-11
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Tomato leaf curl disease (ToLCD) is manifested by yellowing of leaf lamina with upward leaf curl, leaf distortion, shrinking of the leaf surface, and stunted plant growth caused by tomato leaf curl virus (ToLCV).
In the present study, using computational methods we explored the evolutionary and molecular prospects of viral coat protein derived from an isolate of Vadodara district, Gujarat (ToLCGV-[Vad]), India.
We found that the amino acids in coat protein required for systemic infection, viral particle formation, and insect transmission to host cells were conserved amongst Indian strains.
Phylogenetic studies on Indian ToLCV coat proteins showed evolutionary compatibility with other viral taxa.
Modeling of coat protein revealed a topology similar to characteristic Geminate viral particle consisting of antiparallel β-barrel motif with N-terminus α-helix.
The molecular interaction of coat protein with the viral DNA required for encapsidation and nuclear shuttling was investigated through sequence- and structure-based approaches.
We further emphasized the role of loops in coat protein structure as molecular recognition interface.
American Psychological Association (APA)
Kumar, Sivakumar Prasanth& Patel, Saumya K.& Kapopara, Ravi G.& Jasrai, Yogesh T.& Pandya, Himanshu A.. 2012. Evolutionary and Molecular Aspects of Indian Tomato Leaf Curl Virus Coat Protein. International Journal of Plant Genomics،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-470586
Modern Language Association (MLA)
Kumar, Sivakumar Prasanth…[et al.]. Evolutionary and Molecular Aspects of Indian Tomato Leaf Curl Virus Coat Protein. International Journal of Plant Genomics No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-470586
American Medical Association (AMA)
Kumar, Sivakumar Prasanth& Patel, Saumya K.& Kapopara, Ravi G.& Jasrai, Yogesh T.& Pandya, Himanshu A.. Evolutionary and Molecular Aspects of Indian Tomato Leaf Curl Virus Coat Protein. International Journal of Plant Genomics. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-470586
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470586