Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland
Joint Authors
Wojtas-Bonior, Izabela
Skiba, Iwona
Budak, Alicja
Klesiewicz, Karolina
Sito, Edward
Karczewska, Elżbieta
Zwolińska-Wcisło, Małgorzata
Czajecki, Krzysztof
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
An increasing resistance of Helicobacter pylori strains to antimicrobial agents is the serious therapeutic problem.
The aim of this study was to compare the primary and secondary resistance of H.
pylori strains isolated between 2006–2008 (data published) and 2009–2011 to clarithromycin and levofloxacin.
Material and Methods.
220 dyspeptic patients (153 before treatment, 67 after), were enrolled in the study.
51 H.
pylori strains were isolated.
MIC values of clarithromycin and levofloxacin were determined by the E-test method.
The statistical analysis was conducted with the χ2 test with Yates correction at the 0.05 significance level (P≤0.05).
Results.
Between 2006 and 2008, 34% (39/115) of H.
pylori strains were resistant to clarithromycin (primary 21% (19/90), secondary 80% (20/25)).
5% (6/115) of strains were resistant to levofloxacin (primary 2% (2/90), secondary 16% ((4/25); data published) Between 2009–2011, 22% (11/51) of H.
pylori strains were resistant to clarithromycin (primary 19% (8/43), secondary 38% (3/8)).
16% (8/51) of strains were resistant to levofloxacin (primary 12% (5/43), secondary 38% (3/8)).
Conclusion.
The present study has shown the increasing amount of resistant H.
pylori strains isolated from patients in Southern Poland to levofloxacin and decreasing number of resistant strains to clarithromycin.
American Psychological Association (APA)
Karczewska, Elżbieta& Klesiewicz, Karolina& Skiba, Iwona& Wojtas-Bonior, Izabela& Sito, Edward& Czajecki, Krzysztof…[et al.]. 2012. Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-470593
Modern Language Association (MLA)
Karczewska, Elżbieta…[et al.]. Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland. Gastroenterology Research and Practice No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-470593
American Medical Association (AMA)
Karczewska, Elżbieta& Klesiewicz, Karolina& Skiba, Iwona& Wojtas-Bonior, Izabela& Sito, Edward& Czajecki, Krzysztof…[et al.]. Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-470593
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470593