Heart Transplantation in a 14-Year-Old Boy in the Presence of Severe Out-of-Proportion Pulmonary Hypertension due to Restrictive Left Heart Disease : A Case Report
Joint Authors
Schermer, Elisabeth
Irnberger, Erentraud
Geiger, Ralf
Schweigmann, Ulrich
Schwienbacher, Martin
Velik-Salchner, Corinna
Neu, Nikolaus
Michel-Behnke, Ina
Steger, Christina Maria
Stein, Jörg Ingolf
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A 14-year-old boy after balloon valvuloplasty of severe aortic valve stenosis in the neonatal period was referred for heart-lung transplantation because of high grade pulmonary hypertension and left heart dysfunction due to endocardial fibroelastosis with severe mitral insufficiency.
After heart catheterization, hemodynamic parameters were invasively monitored: a course of levosimendan and initiation of diuretics led to a decrease of pulmonary capillary wedge pressure (from maximum 35 to 24 mmHg).
Instead of an expected decrease, mean pulmonary artery pressures (mPAP) increased up to 80 mmHg with increasing transpulmonary pressure gradient (TPG) up to 55 mmHg.
Oral bosentan and intravenous epoprostenol then led to a ~50% decrease of mPAP (TPG between 16 and 22 mmHg).
The boy was listed solely for heart transplantation which was successfully accomplished 1 month later.
American Psychological Association (APA)
Schwienbacher, Martin& Schweigmann, Ulrich& Neu, Nikolaus& Schermer, Elisabeth& Velik-Salchner, Corinna& Michel-Behnke, Ina…[et al.]. 2013. Heart Transplantation in a 14-Year-Old Boy in the Presence of Severe Out-of-Proportion Pulmonary Hypertension due to Restrictive Left Heart Disease : A Case Report. Case Reports in Cardiology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-470651
Modern Language Association (MLA)
Schwienbacher, Martin…[et al.]. Heart Transplantation in a 14-Year-Old Boy in the Presence of Severe Out-of-Proportion Pulmonary Hypertension due to Restrictive Left Heart Disease : A Case Report. Case Reports in Cardiology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-470651
American Medical Association (AMA)
Schwienbacher, Martin& Schweigmann, Ulrich& Neu, Nikolaus& Schermer, Elisabeth& Velik-Salchner, Corinna& Michel-Behnke, Ina…[et al.]. Heart Transplantation in a 14-Year-Old Boy in the Presence of Severe Out-of-Proportion Pulmonary Hypertension due to Restrictive Left Heart Disease : A Case Report. Case Reports in Cardiology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-470651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470651