Influenza Vaccination in the Face of Immune Exhaustion : Is Herd Immunity Effective for Protecting the Elderly?
Joint Authors
Samaras, Nikolaos
Aspinall, Richard
Lang, Pierre Olivier
Govind, Sheila
Samaras, Dimitrios
Source
Influenza Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
At the start of the 21st century, seasonal influenza virus infection is still a major public health concern across the world.
The recent body of evidence confirms that trivalent inactivated influenza vaccines (TIVs) are not optimal within the population who account for approximately 90% of all influenza-related death: elderly and chronically ill individuals regardless of age.
With the ever increasing aging of the world population and the recent fears of any pandemic influenza rife, great efforts and resources have been dedicated to developing more immunogenic vaccines and strategies for enhancing protection in these higher-risk groups.
This paper describes the mechanisms that shape immune response at the extreme ages of life and how they have been taken into account to design more effective immunization strategies for these vulnerable populations.
Furthermore, consideration will be given to how herd immunity may provide an effective strategy in preventing the burden of seasonal influenza infection within the aged population.
American Psychological Association (APA)
Lang, Pierre Olivier& Samaras, Dimitrios& Samaras, Nikolaos& Govind, Sheila& Aspinall, Richard. 2012. Influenza Vaccination in the Face of Immune Exhaustion : Is Herd Immunity Effective for Protecting the Elderly?. Influenza Research and Treatment،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-470718
Modern Language Association (MLA)
Lang, Pierre Olivier…[et al.]. Influenza Vaccination in the Face of Immune Exhaustion : Is Herd Immunity Effective for Protecting the Elderly?. Influenza Research and Treatment No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-470718
American Medical Association (AMA)
Lang, Pierre Olivier& Samaras, Dimitrios& Samaras, Nikolaos& Govind, Sheila& Aspinall, Richard. Influenza Vaccination in the Face of Immune Exhaustion : Is Herd Immunity Effective for Protecting the Elderly?. Influenza Research and Treatment. 2012. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-470718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470718