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The Influence of Hypoxia during Different Pregnancy Stages on Cardiac Collagen Accumulation in the Adult Offspring
Joint Authors
Wang, Lingxing
Wang, Zhenhua
Huang, Ziyang
Li, Meimei
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We evaluated whether the timing of maternal hypoxia during pregnancy influenced cardiac extracellular matrix accumulation in the adult offspring.
Rats in different periods of pregnancy were assigned to maternal hypoxia or control groups.
Maternal hypoxia from day 3 to 21 of pregnancy or day 9 to 21 of pregnancy increased collagen I and collagen III expression in the left ventricle of adult offspring (both P<0.05).
Maternal hypoxia from day 15 to 21 of pregnancy had no effect on adult collagen levels.
Our results indicate that maternal hypoxia at critical windows of cardiovascular development can induce pathological cardiac remodeling in the adult rat offspring.
American Psychological Association (APA)
Wang, Lingxing& Li, Meimei& Huang, Ziyang& Wang, Zhenhua. 2014. The Influence of Hypoxia during Different Pregnancy Stages on Cardiac Collagen Accumulation in the Adult Offspring. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470776
Modern Language Association (MLA)
Wang, Lingxing…[et al.]. The Influence of Hypoxia during Different Pregnancy Stages on Cardiac Collagen Accumulation in the Adult Offspring. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-470776
American Medical Association (AMA)
Wang, Lingxing& Li, Meimei& Huang, Ziyang& Wang, Zhenhua. The Influence of Hypoxia during Different Pregnancy Stages on Cardiac Collagen Accumulation in the Adult Offspring. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-470776
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470776