Intrinsic Ability of Adult Stem Cell in Skeletal Muscle : An Effective and Replenishable Resource to the Establishment of Pluripotent Stem Cells
Joint Authors
Hidaka, Ryo
Asashima, Makoto
Takemasa, Tohru
Machida, Masanao
Fujimaki, Shin
Warashina, Masaki
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-02
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Adult stem cells play an essential role in mammalian organ maintenance and repair throughout adulthood since they ensure that organs retain their ability to regenerate.
The choice of cell fate by adult stem cells for cellular proliferation, self-renewal, and differentiation into multiple lineages is critically important for the homeostasis and biological function of individual organs.
Responses of stem cells to stress, injury, or environmental change are precisely regulated by intercellular and intracellular signaling networks, and these molecular events cooperatively define the ability of stem cell throughout life.
Skeletal muscle tissue represents an abundant, accessible, and replenishable source of adult stem cells.
Skeletal muscle contains myogenic satellite cells and muscle-derived stem cells that retain multipotent differentiation abilities.
These stem cell populations have the capacity for long-term proliferation and high self-renewal.
The molecular mechanisms associated with deficits in skeletal muscle and stem cell function have been extensively studied.
Muscle-derived stem cells are an obvious, readily available cell resource that offers promise for cell-based therapy and various applications in the field of tissue engineering.
This review describes the strategies commonly used to identify and functionally characterize adult stem cells, focusing especially on satellite cells, and discusses their potential applications.
American Psychological Association (APA)
Fujimaki, Shin& Machida, Masanao& Hidaka, Ryo& Asashima, Makoto& Takemasa, Tohru& Warashina, Masaki. 2013. Intrinsic Ability of Adult Stem Cell in Skeletal Muscle : An Effective and Replenishable Resource to the Establishment of Pluripotent Stem Cells. Stem Cells International،Vol. 2013, no. 2013, pp.1-18.
https://search.emarefa.net/detail/BIM-470794
Modern Language Association (MLA)
Fujimaki, Shin…[et al.]. Intrinsic Ability of Adult Stem Cell in Skeletal Muscle : An Effective and Replenishable Resource to the Establishment of Pluripotent Stem Cells. Stem Cells International No. 2013 (2013), pp.1-18.
https://search.emarefa.net/detail/BIM-470794
American Medical Association (AMA)
Fujimaki, Shin& Machida, Masanao& Hidaka, Ryo& Asashima, Makoto& Takemasa, Tohru& Warashina, Masaki. Intrinsic Ability of Adult Stem Cell in Skeletal Muscle : An Effective and Replenishable Resource to the Establishment of Pluripotent Stem Cells. Stem Cells International. 2013. Vol. 2013, no. 2013, pp.1-18.
https://search.emarefa.net/detail/BIM-470794
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470794