Early Stage Oropharyngeal Carcinomas : Comparing Quality of Life for Different Treatment Modalities
Joint Authors
Iro, Heinrich
Psychogios, Georgios
Zenk, Johannes
Grundtner, Philipp
Ryzek, Don-Felix
Künzel, Julian
Mantsopoulos, Konstantinos
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To compare long-term quality of life outcomes after treating early stage oropharyngeal carcinoma either with surgery, surgery combined with radiotherapy, or surgery combined with chemoradiotherapy.
Methods.
Questionnaire based method: 111 eligible patients agreed to fill out a quality of life questionnaire.
Results.
Of the 32 scales contained in the EORTC’s combined QLQ-C30 and HN35, 11 scales show significantly better results for the surgery-only treatment group when compared to either surgery combined with radiotherapy or surgery combined with any type of adjuvant therapy.
These eleven scales are role function (P=0.019/0.008), social function (P=0.01/0.034), nausea (P=0.017/0.025), pain (P=0.014/0.023), financial problems (P=0.030/0.012), speech (P=0.02/0.015), social eating (P=0.003/<0.001), mouth opening (P=0.033/0.016), sticky saliva (P=0.001/<0.001), swallowing (P<0.001/<0.001), and dry mouth (P<0.001/0.001).
Conclusion.
Treatment of early stage oropharyngeal carcinoma with surgery alone has definite advantages over treatments including any form of adjuvant therapy when considering quality of life.
Advantages manifest themselves especially in functional aspects of the head and neck realm; however general health aspects as well as psychosocial aspects show improvements as well.
This study does not show any indication of QOL-related drawbacks of surgery-only treatment approaches.
American Psychological Association (APA)
Ryzek, Don-Felix& Mantsopoulos, Konstantinos& Künzel, Julian& Grundtner, Philipp& Zenk, Johannes& Iro, Heinrich…[et al.]. 2014. Early Stage Oropharyngeal Carcinomas : Comparing Quality of Life for Different Treatment Modalities. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-470972
Modern Language Association (MLA)
Ryzek, Don-Felix…[et al.]. Early Stage Oropharyngeal Carcinomas : Comparing Quality of Life for Different Treatment Modalities. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-470972
American Medical Association (AMA)
Ryzek, Don-Felix& Mantsopoulos, Konstantinos& Künzel, Julian& Grundtner, Philipp& Zenk, Johannes& Iro, Heinrich…[et al.]. Early Stage Oropharyngeal Carcinomas : Comparing Quality of Life for Different Treatment Modalities. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-470972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470972