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A Case of Marine-Lenhart Syndrome with a Negative TSH Receptor Antibody Titer Successfully Treated with a Fixed, Low Dose of I131
Joint Authors
Komatsu, Mitsuhisa
Sato, Yoshihiko
Takei, Masahiro
Ishii, Hiroaki
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We herein describe a case of Marine-Lenhart syndrome with a negative TSH receptor antibody titer.
A 75-year-old female presented to our hospital with malaise, palpitations, and mild fine tremors.
She did not have any signs suggestive of Graves’ ophthalmopathy, including conjunctival injection, periorbital edema, or proptosis.
Her laboratory data were negative for thyroid autoantibodies, including anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies, and anti-TSH receptor antibodies (TRAb).
Ultrasonography of the thyroid gland revealed a tumor in the right lobe.
The remaining thyroid gland had an inhomogeneous and rough texture with a high color Doppler flow.
I123 scintigraphy disclosed a hot nodule in the right thyroid gland corresponding to the tumor detected on ultrasonography, suggesting Plummer disease.
Furthermore, there was an increased uptake of radionuclide in the rest of the thyroid gland, despite the suppressed level of TSH and negative titer of TRAb, suggesting underlying Graves’ disease.
The present findings suggested a diagnosis of Marine-Lenhart syndrome with a negative TRAb titer.
Treatment with 10 mCi of radioiodine was highly effective in treating hyperthyroidism in this case.
A negative TSH receptor antibody titer does not necessarily rule out the existence of Graves’ disease in patients with Plummer disease.
American Psychological Association (APA)
Takei, Masahiro& Ishii, Hiroaki& Sato, Yoshihiko& Komatsu, Mitsuhisa. 2014. A Case of Marine-Lenhart Syndrome with a Negative TSH Receptor Antibody Titer Successfully Treated with a Fixed, Low Dose of I131. Case Reports in Endocrinology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-471012
Modern Language Association (MLA)
Takei, Masahiro…[et al.]. A Case of Marine-Lenhart Syndrome with a Negative TSH Receptor Antibody Titer Successfully Treated with a Fixed, Low Dose of I131. Case Reports in Endocrinology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-471012
American Medical Association (AMA)
Takei, Masahiro& Ishii, Hiroaki& Sato, Yoshihiko& Komatsu, Mitsuhisa. A Case of Marine-Lenhart Syndrome with a Negative TSH Receptor Antibody Titer Successfully Treated with a Fixed, Low Dose of I131. Case Reports in Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-471012
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471012