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Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger
Joint Authors
Source
International Journal of Evolutionary Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The secondary metabolite gene clusters of euascomycete fungi are among the largest known clusters of functionally related genes in eukaryotes.
Most of these clusters are species specific or genus specific, and little is known about how they are formed during evolution.
We used a comparative genomics approach to study the evolutionary origins of a secondary metabolite cluster that synthesizes a polyketide derivative, namely, the fumonisin (FUM) cluster of Fusarium verticillioides, and that of Aspergillus niger another fumonisin (fumonisin B) producing species.
We identified homologs in other euascomycetes of the Fusarium verticillioides FUM genes and their flanking genes.
We discuss four models for the origin of the FUM cluster in Fusarium verticillioides and argue that two of these are plausible: (i) assembly by relocation of initially scattered genes in a recent Fusarium verticillioides; or (ii) horizontal transfer of the FUM cluster from a distantly related Sordariomycete species.
We also propose that the FUM cluster was horizontally transferred into Aspergillus niger, most probably from a Sordariomycete species.
American Psychological Association (APA)
Khaldi, Nora& Wolfe, Kenneth H.. 2011. Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger. International Journal of Evolutionary Biology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471044
Modern Language Association (MLA)
Khaldi, Nora& Wolfe, Kenneth H.. Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger. International Journal of Evolutionary Biology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-471044
American Medical Association (AMA)
Khaldi, Nora& Wolfe, Kenneth H.. Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger. International Journal of Evolutionary Biology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471044
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471044