Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode

Joint Authors

Wu, Liu-Zhen
Zhang, Rong
Li, Hong-Yu
Cui, Cai-Lian
Han, Ji Sheng

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-06-09

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Medicine

Abstract EN

In a previous paper we reported that electroacupuncture (EA) could suppress opioid withdrawal syndrome and increase the appetite, sleep, and body weight in heroin addicts or morphine dependent animals.

Considering that opioids were known to inhibit immune function, the present study was designed to observe whether EA could modulate the immune status of morphine dependent and withdrawal mice.

We found that chronic morphine-induced decrease of splenic T lymphocyte proliferation and IL-2 production can be significantly raised by 2 Hz EA, and the fluctuation of CD4+/CD8+ ratio was also run to the baseline level by the EA.

These findings indicated that chronic morphine exposure-induced immune dysfunction in mice could be normalized by 2 Hz EA.

American Psychological Association (APA)

Li, Hong-Yu& Zhang, Rong& Cui, Cai-Lian& Han, Ji Sheng& Wu, Liu-Zhen. 2011. Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-471068

Modern Language Association (MLA)

Li, Hong-Yu…[et al.]. Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-471068

American Medical Association (AMA)

Li, Hong-Yu& Zhang, Rong& Cui, Cai-Lian& Han, Ji Sheng& Wu, Liu-Zhen. Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-471068

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-471068