Decreased Risk of Squamous Cell Carcinoma of the Head and Neck in Users of Nonsteroidal Anti-Inflammatory Drugs

Joint Authors

Noone, Anne-Michelle
Davidson, Bruce J.
Goldman, Radoslav
Ahmadi, Neda
Seillier-Moiseiwitsch, Françoise
Kosti, Ourania

Source

International Journal of Otolaryngology

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-06-03

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

We evaluated the chemopreventive effect of nonsteroidal anti-inflammatory drug (NSAID) use in head and neck squamous cell carcinomas (HNSCC) by conducting a case-control study based on the administration of a standardized questionnaire to 71 incident HNSCC cases and same number of healthy controls.

NSAID use was associated with a 75% reduction in risk of developing HNSCC.

A significant risk reduction was noted in association with frequency of NSAID use.

Restricting the analysis to aspirin users revealed a significant 90% reduction in risk of developing HNSCC.

This study provides evidence for a significant reduction in the risk of developing HNSCC in users of NSAIDs, and specifically aspirin users.

American Psychological Association (APA)

Ahmadi, Neda& Goldman, Radoslav& Seillier-Moiseiwitsch, Françoise& Noone, Anne-Michelle& Kosti, Ourania& Davidson, Bruce J.. 2010. Decreased Risk of Squamous Cell Carcinoma of the Head and Neck in Users of Nonsteroidal Anti-Inflammatory Drugs. International Journal of Otolaryngology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-471072

Modern Language Association (MLA)

Ahmadi, Neda…[et al.]. Decreased Risk of Squamous Cell Carcinoma of the Head and Neck in Users of Nonsteroidal Anti-Inflammatory Drugs. International Journal of Otolaryngology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-471072

American Medical Association (AMA)

Ahmadi, Neda& Goldman, Radoslav& Seillier-Moiseiwitsch, Françoise& Noone, Anne-Michelle& Kosti, Ourania& Davidson, Bruce J.. Decreased Risk of Squamous Cell Carcinoma of the Head and Neck in Users of Nonsteroidal Anti-Inflammatory Drugs. International Journal of Otolaryngology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-471072

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-471072