Pseudogenes
Author
Source
Comparative and Functional Genomics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Pseudogenes are ubiquitous and abundant in genomes.
Pseudogenes were once called “genomic fossils” and treated as “junk DNA” several years.
Nevertheless, it has been recognized that some pseudogenes play essential roles in gene regulation of their parent genes, and many pseudogenes are transcribed into RNA.
Pseudogene transcripts may also form small interfering RNA or decrease cellular miRNA concentration.
Thus, pseudogenes regulate tumor suppressors and oncogenes.
Their essential functions draw the attention of our research group in my current work on heat shock protein 90: a chaperone of oncogenes.
The paper reviews our current knowledge on pseudogenes and evaluates preliminary results of the chaperone data.
Current efforts to understand pseudogenes interactions help to understand the functions of a genome.
American Psychological Association (APA)
Tutar, Yusuf. 2012. Pseudogenes. Comparative and Functional Genomics،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-471098
Modern Language Association (MLA)
Tutar, Yusuf. Pseudogenes. Comparative and Functional Genomics No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-471098
American Medical Association (AMA)
Tutar, Yusuf. Pseudogenes. Comparative and Functional Genomics. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-471098
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471098