Methylcobalamin : A Potential Vitamin of Pain Killer

Joint Authors

Han, Wenjuan
Hu, Sanjue
Xu, Hui
Zhang, Ming

Source

Neural Plasticity

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-12-26

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

Methylcobalamin (MeCbl), the activated form of vitamin B12, has been used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer’s disease and rheumatoid arthritis.

As an auxiliary agent, it exerts neuronal protection by promoting regeneration of injured nerves and antagonizing glutamate-induced neurotoxicity.

Recently several lines of evidence demonstrated that MeCbl may have potential analgesic effects in experimental and clinical studies.

For example, MeCbl alleviated pain behaviors in diabetic neuropathy, low back pain and neuralgia.

MeCbl improved nerve conduction, promoted the regeneration of injured nerves, and inhibited ectopic spontaneous discharges of injured primary sensory neurons.

This review aims to summarize the analgesic effect and mechanisms of MeCbl at the present.

American Psychological Association (APA)

Zhang, Ming& Han, Wenjuan& Hu, Sanjue& Xu, Hui. 2013. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471107

Modern Language Association (MLA)

Zhang, Ming…[et al.]. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-471107

American Medical Association (AMA)

Zhang, Ming& Han, Wenjuan& Hu, Sanjue& Xu, Hui. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471107

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-471107