Methylcobalamin : A Potential Vitamin of Pain Killer
Joint Authors
Han, Wenjuan
Hu, Sanjue
Xu, Hui
Zhang, Ming
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Methylcobalamin (MeCbl), the activated form of vitamin B12, has been used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer’s disease and rheumatoid arthritis.
As an auxiliary agent, it exerts neuronal protection by promoting regeneration of injured nerves and antagonizing glutamate-induced neurotoxicity.
Recently several lines of evidence demonstrated that MeCbl may have potential analgesic effects in experimental and clinical studies.
For example, MeCbl alleviated pain behaviors in diabetic neuropathy, low back pain and neuralgia.
MeCbl improved nerve conduction, promoted the regeneration of injured nerves, and inhibited ectopic spontaneous discharges of injured primary sensory neurons.
This review aims to summarize the analgesic effect and mechanisms of MeCbl at the present.
American Psychological Association (APA)
Zhang, Ming& Han, Wenjuan& Hu, Sanjue& Xu, Hui. 2013. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471107
Modern Language Association (MLA)
Zhang, Ming…[et al.]. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-471107
American Medical Association (AMA)
Zhang, Ming& Han, Wenjuan& Hu, Sanjue& Xu, Hui. Methylcobalamin : A Potential Vitamin of Pain Killer. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-471107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471107