Frontal Lobe Atrophy in Depression after Stroke
Joint Authors
Wong, Ka Sing
Mok, V. C. T.
Ungvari, Gabor S.
Chu, Winnie Chiu Wing
Lu, J. Y.
Tang, Wai Kwong
Chen, Y. K.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Frontal lobe atrophy (FLA) is associated with late life depression.
However, the role that FLA plays in the development of depression after stroke (DAS) remains unknown.
This study thus examined the association between FLA and DAS.
Methods.
A convenience sample of 705 Chinese patients with acute ischemic stroke admitted to the acute stroke unit of a university-affiliated regional hospital in Hong Kong participated in the study.
A psychiatrist administered the Structural Clinical Interview for DSM-IV to all patients and made a diagnosis of DAS three months after the index stroke.
Results.
Eighty-five (12.1%) patients were diagnosed with DAS.
In univariate analysis, the DAS patients were more likely to have severe FLA (14.1% versus 5.6%).
Severe FLA remained an independent predictor of DAS in multivariate analysis, with an odds ratio of 2.6 (95% confidence intervals = 1.2–5.9).
Conclusions.
The results suggest that FLA may play a role in the pathogenesis of DAS, which supports the hypothesis that cumulative vascular burden may be important in predicting DAS.
Further investigations are needed to clarify the impact of FLA on the clinical presentation, treatment response, and outcome of DAS in stroke survivors.
American Psychological Association (APA)
Tang, Wai Kwong& Chen, Y. K.& Lu, J. Y.& Mok, V. C. T.& Chu, Winnie Chiu Wing& Ungvari, Gabor S.…[et al.]. 2013. Frontal Lobe Atrophy in Depression after Stroke. Stroke Research and Treatment،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-471123
Modern Language Association (MLA)
Tang, Wai Kwong…[et al.]. Frontal Lobe Atrophy in Depression after Stroke. Stroke Research and Treatment No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-471123
American Medical Association (AMA)
Tang, Wai Kwong& Chen, Y. K.& Lu, J. Y.& Mok, V. C. T.& Chu, Winnie Chiu Wing& Ungvari, Gabor S.…[et al.]. Frontal Lobe Atrophy in Depression after Stroke. Stroke Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-471123
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471123