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Breast Cancer Biology : The Multifaceted Roles of Mesenchymal Stem Cells
Joint Authors
Heidaran, Nicole
Reddy, Bobby Y.
Rameshwar, Pranela
Srinivas, Balaji
Heinrich, Andrew C.
Patel, Shyam A.
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-12-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Recent upsurge in the interest of breast cancer metastasis is partly attributed to the discovery of novel, yet unclear, mechanisms of breast cancer interaction with sites of distant metastasis such as the bone marrow microenvironment.
In this review, we discuss the significance of the interactions between breast cancer cells and cells of the bone marrow.
This is a subject of intense research studies aim to provide new methods of treatments and perhaps the identification of new drug targets.
This review also discusses the role of inflammation and the bimodal function of the transforming growth factor-β signaling pathway in the process of tumorigenesis.
We bring attention to future prospects in breast cancer research, including the role of microRNAs in cancer quiescence in the bone marrow and the application of microRNAs to basic science discoveries in oncology.
Finally, we discuss the cancer stem cell hypothesis, which is not a new idea, but has resurged with investigative questions.
American Psychological Association (APA)
Patel, Shyam A.& Heinrich, Andrew C.& Reddy, Bobby Y.& Srinivas, Balaji& Heidaran, Nicole& Rameshwar, Pranela. 2008. Breast Cancer Biology : The Multifaceted Roles of Mesenchymal Stem Cells. Journal of Oncology،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-471222
Modern Language Association (MLA)
Patel, Shyam A.…[et al.]. Breast Cancer Biology : The Multifaceted Roles of Mesenchymal Stem Cells. Journal of Oncology No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-471222
American Medical Association (AMA)
Patel, Shyam A.& Heinrich, Andrew C.& Reddy, Bobby Y.& Srinivas, Balaji& Heidaran, Nicole& Rameshwar, Pranela. Breast Cancer Biology : The Multifaceted Roles of Mesenchymal Stem Cells. Journal of Oncology. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-471222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471222