Microarray Analysis of the Juvenile Hormone Response in Larval Integument of the Silkworm, Bombyx mori
Joint Authors
Cheng, Daojun
Kang, Lixia
Wei, Ling
Meng, Meng
Qian, Wenliang
Xia, Qing-You
Peng, Jian
Source
International Journal of Genomics
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-06
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Juvenile hormone (JH) coordinates with 20-hydroxyecdysone (20E) to regulate larval growth and molting in insects.
However, little is known about how this cooperative control is achieved during larval stages.
Here, we induced silkworm superlarvae by applying the JH analogue (JHA) methoprene and used a microarray approach to survey the mRNA expression changes in response to JHA in the silkworm integument.
We found that JHA application significantly increased the expression levels of most genes involved in basic metabolic processes and protein processing and decreased the expression of genes associated with oxidative phosphorylation in the integument.
Several key genes involved in the pathways of insulin/insulin-like growth factor signaling (IIS) and 20E signaling were also upregulated after JHA application.
Taken together, we suggest that JH may mediate the nutrient-dependent IIS pathway by regulating various metabolic pathways and further modulate 20E signaling.
American Psychological Association (APA)
Cheng, Daojun& Peng, Jian& Meng, Meng& Wei, Ling& Kang, Lixia& Qian, Wenliang…[et al.]. 2014. Microarray Analysis of the Juvenile Hormone Response in Larval Integument of the Silkworm, Bombyx mori. International Journal of Genomics،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-471234
Modern Language Association (MLA)
Cheng, Daojun…[et al.]. Microarray Analysis of the Juvenile Hormone Response in Larval Integument of the Silkworm, Bombyx mori. International Journal of Genomics No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-471234
American Medical Association (AMA)
Cheng, Daojun& Peng, Jian& Meng, Meng& Wei, Ling& Kang, Lixia& Qian, Wenliang…[et al.]. Microarray Analysis of the Juvenile Hormone Response in Larval Integument of the Silkworm, Bombyx mori. International Journal of Genomics. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-471234
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471234