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PICOT : A Multidomain Protein with Multiple Functions
Joint Authors
Isakov, Noah
Pulak, Ranjan Nath
Keselman, Anna
Moyal, Keren
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The PICOT protein possesses three highly conserved regions that include an aminoterminal thioredoxin-like homology domain and a tandem repeat of a carboxyterminal PICOT homology domain with an overall conformation that resembles a glutaredoxin homology domain.
In contrast to the classical dithiol thioredoxins and glutaredoxins, PICOT possesses a single cysteine residue in each of its three domains and is therefore distinct from the classical thioredoxin and glutaredoxin redox enzymes.
Recent studies demonstrated that PICOT is a prerequisite for mouse embryogenesis and participates in several independent biological systems in the adult.
This paper examines advances made over the past few years in understanding the role of PICOT in various biological systems.
American Psychological Association (APA)
Keselman, Anna& Pulak, Ranjan Nath& Moyal, Keren& Isakov, Noah. 2011. PICOT : A Multidomain Protein with Multiple Functions. ISRN Immunology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471248
Modern Language Association (MLA)
Keselman, Anna…[et al.]. PICOT : A Multidomain Protein with Multiple Functions. ISRN Immunology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-471248
American Medical Association (AMA)
Keselman, Anna& Pulak, Ranjan Nath& Moyal, Keren& Isakov, Noah. PICOT : A Multidomain Protein with Multiple Functions. ISRN Immunology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471248