Breast Metastatic Localization of Signet-Ring Cell Gastric Carcinoma

Abstract EN

Metastatic tumors in the breast are quite rare and constitute 0,5 to 6% of all breast malignancies.

They often occur in a polymetastatic context.

Gastrointestinal lesions rarely metastasize to the breast.

The first case of a metastasis deposit to the breast and ovary from gastric signet-ring cell carcinoma was reported in the literature in 1999.

Since this report, only 5 cases have been reported.

We present a case report of a 37-year-old woman who complained of a lump in the left breast.

Two months earlier, the woman underwent a subtotal gastrectomy and a total hysterectomy with double anexectomy, which histologically was diagnosed of gastric signet-ring carcinoma, disseminated with Krukenberg's tumor.

In those days, the patient was following a chemotherapy treatment.

A core needle biopsy of the lesion in left breast revealed cells with signet-ring features, with probably gastric origin.