Depressive Symptoms and 24-Hour Ambulatory Blood Pressure in Africans : The SABPA Study
Joint Authors
Harvey, Brian H.
Frasure-Smith, Nancy
Malan, Nico T.
Lespérance, François
Malan, Leoné
Hamer, Mark
Source
International Journal of Hypertension
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Disturbances in circadian rhythm might play a central role in the neurobiology of depression.
We examined the association between depressive symptoms and 24-hour ambulatory BP in a sample of 405 (197 black and 208 Caucasian) urbanized African teachers aged 25 to 60 yrs (mean 44.6 ± 9.6 yrs).
Depressive symptoms were assessed using the self-administered 9-item Patient Health Questionnaire (PHQ-9).
After adjusting for age, sex, and ethnicity, participants with severe depressive symptoms (PHQ-9 ≥ 15) had higher odds of hypertension defined from ambulatory BP and/or use of antihypertensive medication (odds ratio = 2.19, 95% CI, 1.00–4.90) in comparison to participants with no symptoms.
Compared to Caucasians with no depressive symptoms, those with severe symptoms had blunted nocturnal systolic BP drop of 4.7 mmHg (95% CI, −0.5 to 10.0, P=0.07).
In summary, depressive symptoms were associated with the circadian BP profile in black and Caucasian Africans.
American Psychological Association (APA)
Hamer, Mark& Frasure-Smith, Nancy& Lespérance, François& Harvey, Brian H.& Malan, Nico T.& Malan, Leoné. 2011. Depressive Symptoms and 24-Hour Ambulatory Blood Pressure in Africans : The SABPA Study. International Journal of Hypertension،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-471310
Modern Language Association (MLA)
Hamer, Mark…[et al.]. Depressive Symptoms and 24-Hour Ambulatory Blood Pressure in Africans : The SABPA Study. International Journal of Hypertension No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-471310
American Medical Association (AMA)
Hamer, Mark& Frasure-Smith, Nancy& Lespérance, François& Harvey, Brian H.& Malan, Nico T.& Malan, Leoné. Depressive Symptoms and 24-Hour Ambulatory Blood Pressure in Africans : The SABPA Study. International Journal of Hypertension. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-471310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471310