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Do Other Components of Bedding Dust Affect Sensitisation to House Dust Mites?
Joint Authors
Siebers, Robert
Crane, Julian
Smith, Claire
Stanley, Thorsten
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-11
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Bedding dust is a mixture of many components, of which the house dust mite (HDM) allergen, Der p 1, is the most allergenic.
There has been little work to investigate the effect of other bedding dust components on HDM sensitisation.
The objective of the study was to determine the effect of endotoxin in bedding dust on the allergic response in HDM-sensitised individuals.
Twenty-nine house dust mite-sensitised adults were skin prick and allergen patch tested against a sterile solution of their own bedding dust and against a solution containing the same concentration of Der p 1 as the bedding solution for comparison.
There was no significant difference in wheal size between the diluted house dust mite solution and the bedding dust in spite of their high levels of endotoxin.
Symptomatic subjects had larger, but not statistically significant, responses to commercial house dust mite solution than asymptomatic subjects.
Allergen patch test responses were negative in 22/29 of subjects using either bedding dust solutions or comparable diluted house dust mite solutions.
An individual's own bedding dust does not appear to contain factors that enhance skin prick test or atopy patch test responses to house dust mites.
American Psychological Association (APA)
Smith, Claire& Stanley, Thorsten& Crane, Julian& Siebers, Robert. 2012. Do Other Components of Bedding Dust Affect Sensitisation to House Dust Mites?. ISRN Allergy،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-471326
Modern Language Association (MLA)
Smith, Claire…[et al.]. Do Other Components of Bedding Dust Affect Sensitisation to House Dust Mites?. ISRN Allergy No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-471326
American Medical Association (AMA)
Smith, Claire& Stanley, Thorsten& Crane, Julian& Siebers, Robert. Do Other Components of Bedding Dust Affect Sensitisation to House Dust Mites?. ISRN Allergy. 2012. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-471326
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471326