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Review of Clinical Trials on Effects of Oral Antioxidants on Basic Semen and Other Parameters in Idiopathic Oligoasthenoteratozoospermia
Joint Authors
Pinter, Bojana
Imamovic Kumalic, Senka
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-31
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Infertility affects 50 to 80 million people worldwide.
Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT).
With common diagnostic methods no cause can be found in approximately 30% of cases of male infertility due to OAT and these are considered idiopathic.
Reactive oxygen species (ROS) play an important role in male infertility and are proved to be higher in infertile men; antioxidants could oppose their effect.
The aim of this paper was to review the literature on clinical trials in the period from year 2000 to year 2013 studying the effects of various types of antioxidant supplements on basic and other sperm parameters and pregnancy rates in subfertile males with idiopathic OAT.
The majority of studies were randomized and placebo controlled and confirmed beneficial effect of antioxidants on at least one of the semen parameters; the biggest effect was determined on sperm motility.
In many of these trials combinations of more antioxidants were assessed.
The optimal dosages of one or more antioxidants were not defined.
We concluded that antioxidants play an important role in protecting semen from ROS and can improve basic sperm parameters in case of idiopathic OAT.
American Psychological Association (APA)
Imamovic Kumalic, Senka& Pinter, Bojana. 2014. Review of Clinical Trials on Effects of Oral Antioxidants on Basic Semen and Other Parameters in Idiopathic Oligoasthenoteratozoospermia. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-471327
Modern Language Association (MLA)
Imamovic Kumalic, Senka& Pinter, Bojana. Review of Clinical Trials on Effects of Oral Antioxidants on Basic Semen and Other Parameters in Idiopathic Oligoasthenoteratozoospermia. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-471327
American Medical Association (AMA)
Imamovic Kumalic, Senka& Pinter, Bojana. Review of Clinical Trials on Effects of Oral Antioxidants on Basic Semen and Other Parameters in Idiopathic Oligoasthenoteratozoospermia. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-471327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471327