Goodpasture's Syndrome and Silica : A Case Report and Literature Review
Joint Authors
Peckham, Trevor
Wardenburg, Marla
Dahlgren, James
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We report a case of Goodpasture's syndrome following chronic low level and an acute, high level of exposure to crystalline silica.
A 38-year-old male tilesetter was admitted to the emergency room with dyspnea and respiratory failure.
He reported that his symptoms had developed over the previous week after inhaling a large amount of dust while dry-sanding and sweeping a silica-based product used to fill cracks in a cement floor.
Over the following days, his pulmonary function declined and he developed acute renal failure.
Tests of antiglomerular basement membrane antibody were positive and renal biopsy revealed global glomerulonephritis.
He was diagnosed with Goodpasture's syndrome and treated with steroids, plasmapheresis, and hemodialysis.
This man had a history of childhood asthma and a remote, one pack-year history of cigarette use.
He used the flooring product for seven years prior to the inciting event, however, previous jobs had utilized significantly smaller amounts.
Goodpasture's syndrome and other autoimmune diseases have been reported in association with silica exposure.
The acute onset following high level silica exposure in this previously healthy man, suggest that clinicians should investigate silica exposure as a causal factor in cases of Goodpasture's syndrome.
American Psychological Association (APA)
Dahlgren, James& Wardenburg, Marla& Peckham, Trevor. 2010. Goodpasture's Syndrome and Silica : A Case Report and Literature Review. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-471332
Modern Language Association (MLA)
Dahlgren, James…[et al.]. Goodpasture's Syndrome and Silica : A Case Report and Literature Review. Case Reports in Medicine No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-471332
American Medical Association (AMA)
Dahlgren, James& Wardenburg, Marla& Peckham, Trevor. Goodpasture's Syndrome and Silica : A Case Report and Literature Review. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-471332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471332