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Insulin in the Medical Management of Postprandial Hypoglycemia in a Patient with Type 2 Diabetes after Gastric Bypass Surgery
Joint Authors
Rondinelli-Hamilton, Lara
Koh, Chung-Kay
Baldwin, David
Reddy, Arati
Hor, Tiffany
Schoenberger, Jennifer Leung
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
We evaluated a 47-year-old woman with a history of type 2 diabetes and severe obesity who developed postprandial hypoglycemia after undergoing Roux-en-Y gastric bypass surgery and losing 60% of her total body weight.
We studied her insulin secretion and blood glucose dynamics and were able to tailor a therapeutic regimen involving insulin that eliminated episodes of hypoglycemia.
Methods.
We studied blood glucose levels during a prolonged fast, performed continuous glucose monitoring studies using a subcutaneous glucose sensor, and evaluated regional pancreatic insulin secretion using selective arterial calcium stimulation.
Results.
Continuous glucose monitoring revealed that the patient had early (1-2 hr) postprandial hyperglycemia followed by late (3-4 hr) postprandial hypoglycemia.
Biochemical studies confirmed endogenous pancreatogenous insulin secretion as the cause of episodic hypoglycemia, but imaging studies and selective arterial calcium stimulation failed to localize an insulinoma.
The patient was treated with preprandial doses of insulin aspart in order to attenuate the early postprandial hyperglycemia, and the late hypoglycemic episodes were avoided.
Conclusion.
We describe an interesting and novel nonsurgical approach to the prevention of postprandial hypoglycemia in a patient with noninsulinoma pancreatogenous hypoglycemia after gastric bypass.
American Psychological Association (APA)
Schoenberger, Jennifer Leung& Koh, Chung-Kay& Hor, Tiffany& Baldwin, David& Reddy, Arati& Rondinelli-Hamilton, Lara. 2012. Insulin in the Medical Management of Postprandial Hypoglycemia in a Patient with Type 2 Diabetes after Gastric Bypass Surgery. Case Reports in Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-471390
Modern Language Association (MLA)
Schoenberger, Jennifer Leung…[et al.]. Insulin in the Medical Management of Postprandial Hypoglycemia in a Patient with Type 2 Diabetes after Gastric Bypass Surgery. Case Reports in Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-471390
American Medical Association (AMA)
Schoenberger, Jennifer Leung& Koh, Chung-Kay& Hor, Tiffany& Baldwin, David& Reddy, Arati& Rondinelli-Hamilton, Lara. Insulin in the Medical Management of Postprandial Hypoglycemia in a Patient with Type 2 Diabetes after Gastric Bypass Surgery. Case Reports in Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-471390
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471390