The Role of Physical Exercise in Inflammatory Bowel Disease
Joint Authors
Mazur-Bialy, Agnieszka
Bilski, Jan
Sliwowski, Zbigniew
Brzozowski, Bartosz
Brzozowski, Tomasz
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-30
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
We reviewed and analyzed the relationship between physical exercise and inflammatory bowel disease (IBD) which covers a group of chronic, relapsing, and remitting intestinal disorders including Crohn’s disease (CD) and ulcerative colitis.
The etiology of IBD likely involves a combination of genetic predisposition and environmental risk factors.
Physical training has been suggested to be protective against the onset of IBD, but there are inconsistencies in the findings of the published literature.
Hypertrophy of the mesenteric white adipose tissue (mWAT) is recognized as a characteristic feature of CD, but its importance for the perpetuation of onset of this intestinal disease is unknown.
Adipocytes synthesize proinflammatory and anti-inflammatory cytokines.
Hypertrophy of mWAT could play a role as a barrier to the inflammatory process, but recent data suggest that deregulation of adipokine secretion is involved in the pathogenesis of CD.
Adipocytokines and macrophage mediators perpetuate the intestinal inflammatory process, leading to mucosal ulcerations along the mesenteric border, a typical feature of CD.
Contracting skeletal muscles release biologically active myokines, known to exert the direct anti-inflammatory effects, and inhibit the release of proinflammatory mediators from visceral fat.
Further research is required to confirm these observations and establish exercise regimes for IBD patients.
American Psychological Association (APA)
Bilski, Jan& Brzozowski, Bartosz& Mazur-Bialy, Agnieszka& Sliwowski, Zbigniew& Brzozowski, Tomasz. 2014. The Role of Physical Exercise in Inflammatory Bowel Disease. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-471533
Modern Language Association (MLA)
Bilski, Jan…[et al.]. The Role of Physical Exercise in Inflammatory Bowel Disease. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-471533
American Medical Association (AMA)
Bilski, Jan& Brzozowski, Bartosz& Mazur-Bialy, Agnieszka& Sliwowski, Zbigniew& Brzozowski, Tomasz. The Role of Physical Exercise in Inflammatory Bowel Disease. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-471533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471533