Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life
Joint Authors
Røkke, Ola
Iversen, Knut
Turowski, Gitta Erika
Eide, Geir Egil
Ristesund, Sølvi-May
Olsen, Torill
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
Study the functional results and mucosal changes in the ileal pouch after restorative proctocolectomy with J-reservoir for ulcerative colitis.
Material and Methods.
Followup study of 125 patients with J-reservoir with one disease-specific- and one general (SF-36) quality of life-questionnaire, rectoscopy with biopsies, and stool samples to evaluate inflammation, dysplasia, presence of Helicobacter pylori and calprotectin level.
Results.
Fourteen J-reservoirs were removed or deactivated, leaving 111 patients for followup.
The followup time was 6.8 (1–15) years.
87.4% of the patients were satisfied.
93.1% had some kind of functional restriction: food- (75.5%), social- (28.9%), physical- (37%) or sexual restriction (15.3%).
18.6% had often or sometimes faecal incontinence.
Low daytime faecal frequency was associated with good quality of life.
13 patients (12.6%) had a less favourable result.
There was no pouch-dysplasia.
Calprotectin levels were increased in patients with visible pouch inflammation or history of pouchitis.
HP was diagnosed by RUT in 42.3%, but was not associated with inflammation or pouchitis.
Conclusions.
Most patients were satisfied with the J-reservoir in spite of a high frequency of various restrictions.
12.6% (13 patients) had a less favourable functional result, partly due to a high frequency of defecations, pain, pouchitis and inflammation.
American Psychological Association (APA)
Røkke, Ola& Iversen, Knut& Olsen, Torill& Ristesund, Sølvi-May& Eide, Geir Egil& Turowski, Gitta Erika. 2011. Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life. ISRN Gastroenterology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-471639
Modern Language Association (MLA)
Røkke, Ola…[et al.]. Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life. ISRN Gastroenterology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-471639
American Medical Association (AMA)
Røkke, Ola& Iversen, Knut& Olsen, Torill& Ristesund, Sølvi-May& Eide, Geir Egil& Turowski, Gitta Erika. Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life. ISRN Gastroenterology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-471639
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471639