Long-Term Survival and Improved Quality of Life following Multiple Repeat Gamma Knife Radiosurgeries for Recurrent Glioblastoma Multiforme : A Case Report and Review of the Literature
Joint Authors
Larson, Erik W.
Mackay, Alexander R.
Lee, Christopher M.
Peterson, Halloran E.
Lamoreaux, Wayne T.
Call, Jason A.
Demakas, John J.
Fairbanks, Robert K.
Cooke, Barton S.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The management of glioblastoma multiforme (GBM) is in most cases complex and must be specifically tailored to the needs of the patient with the goals of extended survival and improved quality of life.
Despite advancements in therapy, treatment outcomes remain almost universally poor.
Salvage treatment options for the recurrence of the disease is an area of intense study.
The following case highlights the utility of Gamma Knife Radiosurgery (GKRS) as a salvage treatment.
In this clinical situation, three sequential GKRS treatments led to prolonged survival (beyond four years after diagnosis) and improved quality of life in a patient who was unable to receive further chemotherapy regimens and was unwilling to undergo further aggressive resection.
To date, there have been few reports of three or more sequential GKRS treatment sessions utilized as salvage therapy for recurrent GBM in patients who can no longer tolerate chemotherapy.
This report provides evidence that aggressive local treatment with GKRS at the time of recurrence may be appropriate, depending on a patient’s individual clinical situation, and can lead to prolonged survival and improved quality of life.
American Psychological Association (APA)
Larson, Erik W.& Peterson, Halloran E.& Fairbanks, Robert K.& Lamoreaux, Wayne T.& Mackay, Alexander R.& Call, Jason A.…[et al.]. 2013. Long-Term Survival and Improved Quality of Life following Multiple Repeat Gamma Knife Radiosurgeries for Recurrent Glioblastoma Multiforme : A Case Report and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-471785
Modern Language Association (MLA)
Larson, Erik W.…[et al.]. Long-Term Survival and Improved Quality of Life following Multiple Repeat Gamma Knife Radiosurgeries for Recurrent Glioblastoma Multiforme : A Case Report and Review of the Literature. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-471785
American Medical Association (AMA)
Larson, Erik W.& Peterson, Halloran E.& Fairbanks, Robert K.& Lamoreaux, Wayne T.& Mackay, Alexander R.& Call, Jason A.…[et al.]. Long-Term Survival and Improved Quality of Life following Multiple Repeat Gamma Knife Radiosurgeries for Recurrent Glioblastoma Multiforme : A Case Report and Review of the Literature. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-471785
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471785