Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses.
The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic scaffolding molecules, are under complex regulation and play a crucial role in synaptic connectivity and plasticity, as well as in higher brain functions.
An increasing number of studies have established ubiquitination and proteasome-mediated degradation as universal mechanisms in the control of synaptic protein homeostasis.
In this paper, we focus on the role of the ubiquitin-proteasome system (UPS) in the turnover of major neurotransmitter receptors, including glutamatergic and nonglutamatergic receptors, as well as postsynaptic receptor-interacting proteins.
American Psychological Association (APA)
Lin, Amy W.& Man, Heng-Ye. 2013. Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins. Neural Plasticity،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-471812
Modern Language Association (MLA)
Lin, Amy W.& Man, Heng-Ye. Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins. Neural Plasticity No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-471812
American Medical Association (AMA)
Lin, Amy W.& Man, Heng-Ye. Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-471812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471812