The Role of Uridine Adenosine Tetraphosphate in the Vascular System
Joint Authors
Webb, R. Clinton
Matsumoto, Takayuki
Tostes, Rita C.
Source
Advances in Pharmacological Sciences
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The endothelium plays a pivotal role in vascular homeostasis, and endothelial dysfunction is a major feature of cardiovascular diseases, such as arterial hypertension, atherosclerosis, and diabetes.
Recently, uridine adenosine tetraphosphate (Up4A) has been identified as a novel and potent endothelium-derived contracting factor (EDCF).
Up4A structurally contains both purine and pyrimidine moieties, which activate purinergic receptors.
There is an accumulating body of evidence to show that Up4A modulates vascular function by actions on endothelial and smooth muscle cells.
In this paper, we discuss the effects of Up4A on vascular function and a potential role for Up4A in cardiovascular diseases.
American Psychological Association (APA)
Matsumoto, Takayuki& Tostes, Rita C.& Webb, R. Clinton. 2011. The Role of Uridine Adenosine Tetraphosphate in the Vascular System. Advances in Pharmacological Sciences،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471993
Modern Language Association (MLA)
Matsumoto, Takayuki…[et al.]. The Role of Uridine Adenosine Tetraphosphate in the Vascular System. Advances in Pharmacological Sciences No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-471993
American Medical Association (AMA)
Matsumoto, Takayuki& Tostes, Rita C.& Webb, R. Clinton. The Role of Uridine Adenosine Tetraphosphate in the Vascular System. Advances in Pharmacological Sciences. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-471993
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-471993