Modifiable Risk Factors for Early Mortality on Hemodialysis
Joint Authors
McQuillan, Rory
Lok, Charmaine E.
Fenton, Stanley
Trpeski, Lilyanna
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Data of incident hemodialysis patients from 2001 to 2007 were abstracted from The Renal Disease Registry (TRDR) from central Ontario, Canada and followed until December 2008 to determine 90-day mortality rates for incident hemodialysis patients.
Modifiable risk factors of early mortality were determined by a Cox model.
In total, 876 of 4807 incident patients died during their first year on dialysis; 304 (34.7%) deaths occurred within the first 90 days of dialysis initiation.
The majority of deaths were attributed to a cardiovascular event or infection and more likely occurred in older patients and those with cardiovascular co-morbidities.
Of potentially modifiable risk factors, low body mass index (<18.5), a surrogate for malnutrition, was a strong predictor of early mortality [adjusted hazard ratio (HR) 4.22 (CI: 3.12–5.17)].
Also, central venous catheter use was associated with a 2.40 fold increase risk of death (CI: 1.4–3.90).
Patients who attended a multidisciplinary pre-dialysis clinic were less likely to die (HR: 0.60, CI: 0.47–0.78).
The first 90 days after initiation of dialysis is a period of especially high risk of death.
We have identified potentially modifiable risk factors in vascular access type, pre-dialysis care and nutritional status.
American Psychological Association (APA)
McQuillan, Rory& Trpeski, Lilyanna& Fenton, Stanley& Lok, Charmaine E.. 2012. Modifiable Risk Factors for Early Mortality on Hemodialysis. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-472056
Modern Language Association (MLA)
McQuillan, Rory…[et al.]. Modifiable Risk Factors for Early Mortality on Hemodialysis. International Journal of Nephrology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-472056
American Medical Association (AMA)
McQuillan, Rory& Trpeski, Lilyanna& Fenton, Stanley& Lok, Charmaine E.. Modifiable Risk Factors for Early Mortality on Hemodialysis. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-472056
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472056