Cytokine-Induced NK-Like T Cells : From Bench to Bedside

Joint Authors

Hui, Kam M.
Linn, Yeh Ching

Source

Journal of Biomedicine and Biotechnology

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-03-30

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

Cytokine-induced killer (CIK) cells are polyclonal T effector cells generated when cultured under cytokine stimulation.

CIK cells exhibit potent, non-MHC-restricted cytolytic activities against susceptible tumor cells of both autologous and allogeneic origins.

Over the past 20 years, CIK cells have evolved from experimental observations into early clinical studies with encouraging preliminary efficacy towards susceptible autologous and allogeneic tumor cells in both therapeutic and adjuvant settings.

This paper is our attempt to summarize the available published literature related to CIK cells.

Looking into the future, we anticipate that the continuous therapeutic application of CIK cells will likely be developed along two major directions: overcoming the challenge to organize large prospective randomized clinical trials to define the roles of CIK cells in cancer immunotherapy and expanding its spectrum of cytotoxicity towards resistant tumor cells through experimental manipulations.

American Psychological Association (APA)

Linn, Yeh Ching& Hui, Kam M.. 2010. Cytokine-Induced NK-Like T Cells : From Bench to Bedside. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-472057

Modern Language Association (MLA)

Linn, Yeh Ching& Hui, Kam M.. Cytokine-Induced NK-Like T Cells : From Bench to Bedside. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-472057

American Medical Association (AMA)

Linn, Yeh Ching& Hui, Kam M.. Cytokine-Induced NK-Like T Cells : From Bench to Bedside. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-472057

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-472057