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Nonsteroidal Anti-Inflammatory Drugs and Prostatic Diseases
Joint Authors
Ishiguro, Hitoshi
Kawahara, Takashi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Prostatic diseases are characterized by increased activity of cytokines, growth factors, and cyclooxygenases- (COX-) 1 and 2.
Activation of COX-1 and COX-2 results in increased levels of prostaglandins and the induction of angiogenic, antiapoptotic and inflammatory processes.
Inhibition of COX enzymes by members of the widely used nonsteroidal anti-inflammatory drug (NSAID) class of drugs decreases prostaglandin production, and exerts a variety of anti-inflammatory, antipyretic, and antinociceptive effects.
While numerous in vitro, in vivo, and clinical studies have shown that NSAIDs inhibit the risk and progression of prostatic diseases, the relationship between NSAIDs and such diseases remains controversial.
Here we review the literature in this area, critically analyzing the benefits and caveats associated with the use of NSAIDs in the treatment of prostatic diseases.
American Psychological Association (APA)
Ishiguro, Hitoshi& Kawahara, Takashi. 2014. Nonsteroidal Anti-Inflammatory Drugs and Prostatic Diseases. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-472101
Modern Language Association (MLA)
Ishiguro, Hitoshi& Kawahara, Takashi. Nonsteroidal Anti-Inflammatory Drugs and Prostatic Diseases. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-472101
American Medical Association (AMA)
Ishiguro, Hitoshi& Kawahara, Takashi. Nonsteroidal Anti-Inflammatory Drugs and Prostatic Diseases. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-472101
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472101