![](/images/graphics-bg.png)
Autophagy in Hepatic Fibrosis
Joint Authors
Xiao, Junjie
Zhao, Yingying
Yang, Changqing
Song, Yang
Tao, Lichan
Wang, Fei
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Hepatic fibrosis is a leading cause of morbidity and mortality worldwide.
Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances.
Effective clinical therapies are still lacking.
Autophagy is a cellular process that degrades damaged organelles or protein aggregation, which participates in many pathological processes including liver diseases.
Autophagy participates in hepatic fibrosis by activating hepatic stellate cells and may participate as well through influencing other fibrogenic cells.
Besides that, autophagy can induce some liver diseases to develop while it may play a protective role in hepatocellular abnormal aggregates related liver diseases and reduces fibrosis.
With a better understanding of the potential effects of autophagy on hepatic fibrosis, targeting autophagy might be a novel therapeutic strategy for hepatic fibrosis in the near future.
American Psychological Association (APA)
Song, Yang& Zhao, Yingying& Wang, Fei& Tao, Lichan& Xiao, Junjie& Yang, Changqing. 2014. Autophagy in Hepatic Fibrosis. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-472117
Modern Language Association (MLA)
Song, Yang…[et al.]. Autophagy in Hepatic Fibrosis. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-472117
American Medical Association (AMA)
Song, Yang& Zhao, Yingying& Wang, Fei& Tao, Lichan& Xiao, Junjie& Yang, Changqing. Autophagy in Hepatic Fibrosis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-472117
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472117