Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit : A Five Years Survey
Joint Authors
Devos, Patick
Boussekey, Nicolas
Leroy, Olivier
Georges, Hugues
Langlois, Joachim
Cantrel, Juliette
Dorchin Debrabant, Lise
Chiche, Arnaud
Meybeck, Agnes
Source
Critical Care Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate the epidemiology, prognosis, and management of septic shock patients hospitalized in our intensive care unit (ICU).
Materiel and Methods.
Five-year monocenter observational study including 320 patients.
Results.
ICU mortality was 54.4%.
Independent mortality risk factors were mechanical ventilation (OR=4.97), Simplify Acute Physiology Score (SAPS) II > 60 (OR=4.28), chronic alcoholism (OR=3.38), age >65 years (OR=2.65), prothrombin ratio <40% (OR=2.37), and PaO2/FiO2 ratio <150 (OR=1.91).
These six mortality risk factors recovered allow screening immediately septic shock patients with a high mortality risk.
Morbidity improved with time (diminution of septic shock complications, increase of the number of days alive free from mechanical ventilation and vasopressors on day 28), concomitant to an evolution of the management (earlier institution of all replacement and medical therapies and more initial volume expansion).
There was no difference in mortality.
Conclusion.
Our study confirms a high mortality rate in septic shock patients despite a new approach of treatment.
American Psychological Association (APA)
Boussekey, Nicolas& Cantrel, Juliette& Dorchin Debrabant, Lise& Langlois, Joachim& Devos, Patick& Meybeck, Agnes…[et al.]. 2010. Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit : A Five Years Survey. Critical Care Research and Practice،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-472144
Modern Language Association (MLA)
Boussekey, Nicolas…[et al.]. Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit : A Five Years Survey. Critical Care Research and Practice No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-472144
American Medical Association (AMA)
Boussekey, Nicolas& Cantrel, Juliette& Dorchin Debrabant, Lise& Langlois, Joachim& Devos, Patick& Meybeck, Agnes…[et al.]. Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit : A Five Years Survey. Critical Care Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-472144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472144