A Review of Hot-Melt Extrusion : Process Technology to Pharmaceutical Products
Joint Authors
Boateng, Joshua S.
Maniruzzaman, Mohammed
Snowden, Martin J.
Douroumis, Dennis
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-27
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research developments.
HME has already been demonstrated as a robust, novel technique to make solid dispersions in order to provide time controlled, modified, extended, and targeted drug delivery resulting in improved bioavailability as well as taste masking of bitter active pharmaceutical ingredients (APIs).
This paper reviews the innumerable benefits of HME, based on a holistic perspective of the equipment, processing technologies to the materials, novel formulation design and developments, and its varied applications in oral drug delivery systems.
American Psychological Association (APA)
Maniruzzaman, Mohammed& Boateng, Joshua S.& Snowden, Martin J.& Douroumis, Dennis. 2012. A Review of Hot-Melt Extrusion : Process Technology to Pharmaceutical Products. ISRN Pharmaceutics،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-472175
Modern Language Association (MLA)
Maniruzzaman, Mohammed…[et al.]. A Review of Hot-Melt Extrusion : Process Technology to Pharmaceutical Products. ISRN Pharmaceutics No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-472175
American Medical Association (AMA)
Maniruzzaman, Mohammed& Boateng, Joshua S.& Snowden, Martin J.& Douroumis, Dennis. A Review of Hot-Melt Extrusion : Process Technology to Pharmaceutical Products. ISRN Pharmaceutics. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-472175
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472175