A Unique Case of Malignant Pleuropericardial Effusion : HHV-8-Unrelated PEL-Like Lymphoma—A Case Report and Review of the Literature
Joint Authors
Odaimi, Marcel
Siddiqui, Faraz
Siddique, Muhammad Neaman
Asgari, Masoud
Mohammad, Farhan
Popalzai, M.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Primary effusion lymphoma (PEL) or body cavity lymphoma is a rare type of extra nodal lymphoma of B-cell origin that presents as lymphomatous effusion(s) without any nodal enlargement or tumor masses.
It belongs to the group of AIDS related non-Hodgkin’s lymphomas.
First described in 1996 in HIV infected individuals who were coinfected with Kaposi’s sarcoma-associated herpesvirus (KSHV) or HHV-8 virus, it was included as a separate entity in WHO classification of tumors of hematopoietic and lymphoid tissue in the year 2001.
The definition included association with HHV-8 virus as a mandatory diagnostic criterion.
However, cases were later reported where PEL-like disease process was diagnosed in HHV-8 negative patients.
This was eventually recognized as a rare but distinct entity termed as “HHV-8-unrelated PEL-like lymphoma”.
Herein, we are reporting a case of an elderly patient who presented with a large pleuropericardial effusion and was eventually diagnosed with this entity.
Till date, only around 50 cases of HHV-8-unrelated PEL-like lymphoma have been reported and our case being EBV, HIV, and Hepatitis C negative makes it very unique and rare occurrence.
We are also presenting a review of relevant literature focused mainly on comparing outcomes in patients treated with and without chemotherapy.
American Psychological Association (APA)
Mohammad, Farhan& Siddique, Muhammad Neaman& Siddiqui, Faraz& Popalzai, M.& Asgari, Masoud& Odaimi, Marcel. 2014. A Unique Case of Malignant Pleuropericardial Effusion : HHV-8-Unrelated PEL-Like Lymphoma—A Case Report and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-472179
Modern Language Association (MLA)
Mohammad, Farhan…[et al.]. A Unique Case of Malignant Pleuropericardial Effusion : HHV-8-Unrelated PEL-Like Lymphoma—A Case Report and Review of the Literature. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-472179
American Medical Association (AMA)
Mohammad, Farhan& Siddique, Muhammad Neaman& Siddiqui, Faraz& Popalzai, M.& Asgari, Masoud& Odaimi, Marcel. A Unique Case of Malignant Pleuropericardial Effusion : HHV-8-Unrelated PEL-Like Lymphoma—A Case Report and Review of the Literature. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-472179
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472179