Extramedullary Plasmacytoma of the Larynx : A Case Report of Subglottic Localization

Abstract EN

Extramedullary plasmacytoma (EMP) is a rare neoplasm of plasma cells, described in soft tissue outside the bone marrow.

EMP of the larynx represents 0.04 to 0.45% of malignant tumors of the larynx.

A male of 57 years old presented with hoarseness, dyspnea, and biphasic stridor of 2 months.

The indirect laryngoscopy (IL) revealed severe edema of the posterior commissure and a polypoid mass in the right posterior lateral subglottic wall.

A biopsy of the subglottic mass was performed by a direct laryngoscopy (DL).

The histopathologic diagnosis was EMP CD138+, therefore radiotherapy was given at 54 Gy in 30 sessions.

The patient had an adequate postoperative clinical course and a new biopsy was performed having tumor-free margins.

All laryngeal lesions should be biopsied prior to treatment to determine an accurate diagnosis to guide a proper management of the condition.

Radiation therapy to the EMP is considered the treatment of choice, having local control rates of 80% to 100%.

The subglottis is the least accessible area of view and the least frequent location of a laryngeal mass, nevertheless the otolaryngologist should always do a complete and systematic exam of the larynx when a tumor is suspected, to detect diagnoses such as a subglottic plasmacytoma.