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Big Data Analytics in Immunology : A Knowledge-Based Approach
Joint Authors
Chitkushev, Lou
Zhang, Guang Lan
Sun, Jing
Brusic, Vladimir
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
With the vast amount of immunological data available, immunology research is entering the big data era.
These data vary in granularity, quality, and complexity and are stored in various formats, including publications, technical reports, and databases.
The challenge is to make the transition from data to actionable knowledge and wisdom and bridge the knowledge gap and application gap.
We report a knowledge-based approach based on a framework called KB-builder that facilitates data mining by enabling fast development and deployment of web-accessible immunological data knowledge warehouses.
Immunological knowledge discovery relies heavily on both the availability of accurate, up-to-date, and well-organized data and the proper analytics tools.
We propose the use of knowledge-based approaches by developing knowledgebases combining well-annotated data with specialized analytical tools and integrating them into analytical workflow.
A set of well-defined workflow types with rich summarization and visualization capacity facilitates the transformation from data to critical information and knowledge.
By using KB-builder, we enabled streamlining of normally time-consuming processes of database development.
The knowledgebases built using KB-builder will speed up rational vaccine design by providing accurate and well-annotated data coupled with tailored computational analysis tools and workflow.
American Psychological Association (APA)
Zhang, Guang Lan& Sun, Jing& Chitkushev, Lou& Brusic, Vladimir. 2014. Big Data Analytics in Immunology : A Knowledge-Based Approach. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472316
Modern Language Association (MLA)
Zhang, Guang Lan…[et al.]. Big Data Analytics in Immunology : A Knowledge-Based Approach. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-472316
American Medical Association (AMA)
Zhang, Guang Lan& Sun, Jing& Chitkushev, Lou& Brusic, Vladimir. Big Data Analytics in Immunology : A Knowledge-Based Approach. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472316