Regulation of T Helper 17 by Bacteria : An Approach for the Treatment of Hepatocellular Carcinoma
Joint Authors
Lee, Nikki Pui-yue
El-Nezami, Hani
Sung, Cecilia Ying Ju
Source
International Journal of Hepatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
T helper 17 (TH17) is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment.
Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis.
The origin of tumor-associated TH17 may be related to the gut, in which the differentiation of T cells, especially TH17 cells, is affected by microbiota.
As TH17 may appear to be a new therapeutic target against tumor-promoting inflammation, strategies such as using probiotics to polarize the response away from TH17 may be beneficial to slow down tumor progression.
This paper will attempt to discuss the potential linkage between HCC progression, TH17, and gut microbiota and the possible therapeutic implications of probiotics to modulate TH17-mediated response for tumor growth.
American Psychological Association (APA)
Sung, Cecilia Ying Ju& Lee, Nikki Pui-yue& El-Nezami, Hani. 2012. Regulation of T Helper 17 by Bacteria : An Approach for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-472401
Modern Language Association (MLA)
Sung, Cecilia Ying Ju…[et al.]. Regulation of T Helper 17 by Bacteria : An Approach for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-472401
American Medical Association (AMA)
Sung, Cecilia Ying Ju& Lee, Nikki Pui-yue& El-Nezami, Hani. Regulation of T Helper 17 by Bacteria : An Approach for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-472401
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472401