Rejuvenating of Kidney Tissues on Alloxan Induced Diabetic Mice under the Effect of Momordica charantia
Joint Authors
Jasuja, Nakuleshwar Dut
Sharma, Bhaskar
Sharma, Gaurav
Kumari, Arti
Ram, Gurudayal
Yadav, Ranjeet Kumar
Siddiqui, Mohd. Sufiyan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Diabetes mellitus is a chronic disorder in human and responsible for different complications and also causes mortality and morbidity.
A wide number of herbal products are employed in the treatment of diabetes for their better efficacy and safety compared to synthetic medicine.
The present studies have established the antidiabetic potential and rejuvenating capacity of kidney tissues under the effect of extract.
Diabetes was induced in the Swiss albino mice by injecting alloxan at the dose of 150 mg/kg body weight and aqueous extract of Momordica charantia fruits at doses of 100 mg/kg body weight and 250 mg/kg body weight was administered orally for three weeks.
After 21 days of treatment of the aqueous extracts of Momordica charantia significantly reduces serum glucose level, kidney function tests, lipid peroxidation as well as histopathological study also did show adverse alternation in the morphological architecture of the kidney tissue.
Thus, from this study we concluded that Momordica charantia exhibited significant antihyperglycemic and rejuvenating capacity of kidney tissues activities in alloxan induced diabetic mice.
American Psychological Association (APA)
Sharma, Bhaskar& Siddiqui, Mohd. Sufiyan& Ram, Gurudayal& Yadav, Ranjeet Kumar& Kumari, Arti& Sharma, Gaurav…[et al.]. 2014. Rejuvenating of Kidney Tissues on Alloxan Induced Diabetic Mice under the Effect of Momordica charantia. Advances in Pharmaceutics،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472421
Modern Language Association (MLA)
Sharma, Bhaskar…[et al.]. Rejuvenating of Kidney Tissues on Alloxan Induced Diabetic Mice under the Effect of Momordica charantia. Advances in Pharmaceutics No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-472421
American Medical Association (AMA)
Sharma, Bhaskar& Siddiqui, Mohd. Sufiyan& Ram, Gurudayal& Yadav, Ranjeet Kumar& Kumari, Arti& Sharma, Gaurav…[et al.]. Rejuvenating of Kidney Tissues on Alloxan Induced Diabetic Mice under the Effect of Momordica charantia. Advances in Pharmaceutics. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-472421
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472421