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Distribution of Cytoskeletal Components in Endothelial Cells in the Guinea Pig Renal Artery
Joint Authors
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The cytoskeletal components of endothelial cells in the renal artery were examined by analysis of en face preparations under confocal laser scanning microscopy.
Renal arterial endothelial cells were shown to be elongated along the direction of blood flow, while stress fibers ran perpendicular to the flow in the basal portion.
Focal adhesions were observed along the stress fibers in dot-like configurations.
On the other hand, stress fibers in the apical portion of cells ran along the direction of flow.
The localizations of stress fibers and focal adhesions in endothelial cells in the renal artery differed from those of unperturbed aortic and venous endothelial cells.
Tyrosine-phosphorylated proteins were mainly detected at the sites of cell-to-cell apposition, but not in focal adhesions.
Pulsatile pressure and fluid shear stress applied over endothelial cells in the renal artery induce stress fiber organization and localization of focal adhesions.
These observations suggest that the morphological alignment of endothelial cells along the direction of blood flow and the organization of cytoskeletal components are independently regulated.
American Psychological Association (APA)
Katoh, Kazuo& Noda, Yasuko. 2012. Distribution of Cytoskeletal Components in Endothelial Cells in the Guinea Pig Renal Artery. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-472442
Modern Language Association (MLA)
Katoh, Kazuo& Noda, Yasuko. Distribution of Cytoskeletal Components in Endothelial Cells in the Guinea Pig Renal Artery. International Journal of Cell Biology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-472442
American Medical Association (AMA)
Katoh, Kazuo& Noda, Yasuko. Distribution of Cytoskeletal Components in Endothelial Cells in the Guinea Pig Renal Artery. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-472442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472442